omega-Conotoxin MVIIA (omega conotoxin MVIIA)

Produktnummer ABIN1540040

Kurzübersicht für omega-Conotoxin MVIIA (omega conotoxin MVIIA) (ABIN1540040)

Target: omega-Conotoxin MVIIA

Applikation: Blocking Reagent (BR)

Produktdetails

Verwendungszweck: omega-Conotoxin MVIIA is a Cav2.2 channel blocker

Sequenz: Cys1-Lys-Gly-Lys-Gly-Ala-Lys-Cys8-Ser-Arg-Leu-Met-Tyr-Asp-Cys15-Cys16-Thr-Gly-Ser-Cys20-Arg-Ser-Gly-Lys-Cys25-NH2Disulfide bonds between Cys1-Cys16, Cys8-Cys20and Cys15-Cys25

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Antigendetails

Target: omega-Conotoxin MVIIA

Hintergrund: Omega-Conotoxin MVIIA has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). This toxin blocks N-type calcium channels (Cav2.2/CACNA1B). Omega-conotoxin MVIIA is available under the name Prialt by Neurex. It blocks acute pain in patients who no longer obtain relief from opiate drugs. It is 100 to 1.000 times more potent than morphine. This toxin blocks calcium channels and disables nerves that transmit pain signals.

Molekulargewicht: 2639.18 Da

CAS-Nummer: 107452-89-1